Oral peptide · GLP-1 support

Turn down the food noise.

Signal is a daily yeast-peptide tablet made to support your body's own fullness signal, GLP-1.* No needles. No prescription.

560 mg
yeast peptide

Oratide Signal — GLP-1 Support Tablets

2 tablets
a day

  • 60-day money-back guarantee
  • Free US shipping
  • No stimulants

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Oral peptide

Not a fat burner.
Not a drug.
A daily peptide.

Signal is one ingredient: a peptide made with yeast, in a tablet you take with water. No stimulants, no needles, no prescription, and every amount printed on the front of the bottle.

How Signal works
  • 1 Ingredient, amount printed on the front
  • 0 Stimulants, needles or prescriptions
  • 560 mg Yeast peptide per serving
  • 60 Days to decide, money back

The science

Inside every tablet.

One ingredient, made to work with your body's own fullness signaling, not to override it.*

Two white oblong Signal tablets on warm stone

Yeast peptide

A peptide made with yeast, built around your own fullness signal.*

Signal's one ingredient is a peptide made with Saccharomyces cerevisiae, the yeast species behind bread and beer. It's made to support the cells in your gut that release GLP-1 after you eat, the hormone that tells your brain a meal has landed.*

Read the science

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

GLP-1 support · oral peptide tablets

Signal

Two tablets a day of a 560 mg yeast peptide, made to support the signal your gut sends when you've had enough.*

Skip, change or cancel any time.

Choose your supply
  • 60-day money-back guarantee, even on an empty bottle
  • Free US shipping · most orders leave Florida the same business day
  • 1 ingredient · 60 tablets per bottle · no stimulants
See everything about Signal

Food noise

The voice that keeps bringing up the snack drawer.

Food noise is the running commentary about food that carries on after you've eaten. Appetite isn't only willpower. It runs on signals between your gut and your brain.

GLP-1 is one of the messages your gut sends when a meal arrives. Among other things, it tells your brain you've had enough. Signal is made to support that message, not to replace it.*

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Food noise Loud

An illustration of the idea, not a measurement. Everyone responds differently.

Side by side

The same 560 mg. A fairer deal.

The best-known GLP-1 supplement uses the same amount of yeast peptide per serving. Here's what's different.

Compared Oratide Signal Leading GLP-1 supplement
Yeast peptide per serving 560 mg 560 mg
One bottle, 30 days $148 $148
Subscribe & Save 15% off 15% off
Money back if it isn't for you 60 days, even on an empty bottle No returns or refunds
Free US shipping Yes Yes

† Figures as published on the leading brand's own product page and refund policy, checked 4 October 2026.

Made for you

Find your fit.

  1. 01The GLP-1 curious

    Interested in GLP-1. Not ready for a prescription or a needle.

    Sound familiar
    You want something simple you can take with breakfast and forget about.
    Where Signal fits
    A daily tablet made to support your body's own GLP-1 signaling.*
    This sounds like me
  2. 02The grazer

    Meals are fine. It's everything in between.

    Sound familiar
    The snack drawer, the evening fridge visit, the second helping you didn't really want.
    Where Signal fits
    Made to help quiet cravings between meals.*
    This sounds like me
  3. 03The long game

    You want steady, not another quick fix.

    Sound familiar
    You've tried the stimulant route and the crash that came with it.
    Where Signal fits
    No stimulants, made to support fullness over months, not days.*
    This sounds like me

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

60-second self-check

How loud is your food noise?

Four quick questions. At the end you'll get a suggestion for how long to give Signal.

A self-check, not a medical assessment. Nothing you tap here is saved or sent anywhere.

Question 1 of 4 How often do you think about food when you aren't hungry?
Papers, reading glasses, coffee and a bottle of Oratide Signal on an oak desk

From the founders

We kept seeing supplement labels with 2,500% of something and no reason why. So we asked one question: why can't an ingredients list just be boring?
The founders of OratideBackgrounds in medicine and nutrition
Read our story
Woman in a linen shirt holding a bottle of Oratide Signal

Questions

Your questions, answered.

What is Signal?

A dietary supplement: two tablets a day of a 560 mg yeast peptide, made to support your body's own GLP-1 signaling, appetite and fullness.*

Is it a drug?

No. It contains no prescription GLP-1 medicine and doesn't replace one. You don't need a prescription to buy it.

How do I take it?

Two tablets once a day with water. You can go up to three a day. One bottle lasts 30 days.

When will I notice something?

Everyone is different, and we won't promise a day. That's why the guarantee runs for 60 days.

What if it isn't for me?

Send back what's left within 60 days of your billing date, even an empty bottle, for a full refund of the product price.

How is it different from fat burners?

No stimulants, no caffeine, no green tea extract. Signal is a peptide made to support your own fullness signaling.*

See all questions

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.