Oral peptide · GLP-1 support
Turn down the food noise.
Signal is a daily yeast-peptide tablet made to support your body's own fullness signal, GLP-1.* No needles. No prescription.
- 60-day money-back guarantee
- Free US shipping
- No stimulants
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Oral peptide
Not a fat burner.
Not a drug.
A daily peptide.
Signal is one ingredient: a peptide made with yeast, in a tablet you take with water. No stimulants, no needles, no prescription, and every amount printed on the front of the bottle.
- 1 Ingredient, amount printed on the front
- 0 Stimulants, needles or prescriptions
- 560 mg Yeast peptide per serving
- 60 Days to decide, money back
The science
Inside every tablet.
One ingredient, made to work with your body's own fullness signaling, not to override it.*
Yeast peptide
A peptide made with yeast, built around your own fullness signal.*
Signal's one ingredient is a peptide made with Saccharomyces cerevisiae, the yeast species behind bread and beer. It's made to support the cells in your gut that release GLP-1 after you eat, the hormone that tells your brain a meal has landed.*
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
GLP-1 support · oral peptide tablets
Signal
Two tablets a day of a 560 mg yeast peptide, made to support the signal your gut sends when you've had enough.*
- 60-day money-back guarantee, even on an empty bottle
- Free US shipping · most orders leave Florida the same business day
- 1 ingredient · 60 tablets per bottle · no stimulants
Food noise
The voice that keeps bringing up the snack drawer.
Food noise is the running commentary about food that carries on after you've eaten. Appetite isn't only willpower. It runs on signals between your gut and your brain.
GLP-1 is one of the messages your gut sends when a meal arrives. Among other things, it tells your brain you've had enough. Signal is made to support that message, not to replace it.*
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
An illustration of the idea, not a measurement. Everyone responds differently.
Side by side
The same 560 mg. A fairer deal.
The best-known GLP-1 supplement uses the same amount of yeast peptide per serving. Here's what's different.
| Compared | Oratide Signal | Leading GLP-1 supplement |
|---|---|---|
| Yeast peptide per serving | 560 mg | 560 mg |
| One bottle, 30 days | $148 | $148 |
| Subscribe & Save | 15% off | 15% off |
| Money back if it isn't for you | 60 days, even on an empty bottle | No returns or refunds |
| Free US shipping | Yes | Yes |
† Figures as published on the leading brand's own product page and refund policy, checked 4 October 2026.
Made for you
Find your fit.
-
01The GLP-1 curious
Interested in GLP-1. Not ready for a prescription or a needle.
- Sound familiar
- You want something simple you can take with breakfast and forget about.
- Where Signal fits
- A daily tablet made to support your body's own GLP-1 signaling.*
-
02The grazer
Meals are fine. It's everything in between.
- Sound familiar
- The snack drawer, the evening fridge visit, the second helping you didn't really want.
- Where Signal fits
- Made to help quiet cravings between meals.*
-
03The long game
You want steady, not another quick fix.
- Sound familiar
- You've tried the stimulant route and the crash that came with it.
- Where Signal fits
- No stimulants, made to support fullness over months, not days.*
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
From the founders
We kept seeing supplement labels with 2,500% of something and no reason why. So we asked one question: why can't an ingredients list just be boring?

Questions
Your questions, answered.
What is Signal?
A dietary supplement: two tablets a day of a 560 mg yeast peptide, made to support your body's own GLP-1 signaling, appetite and fullness.*
Is it a drug?
No. It contains no prescription GLP-1 medicine and doesn't replace one. You don't need a prescription to buy it.
How do I take it?
Two tablets once a day with water. You can go up to three a day. One bottle lasts 30 days.
When will I notice something?
Everyone is different, and we won't promise a day. That's why the guarantee runs for 60 days.
What if it isn't for me?
Send back what's left within 60 days of your billing date, even an empty bottle, for a full refund of the product price.
How is it different from fat burners?
No stimulants, no caffeine, no green tea extract. Signal is a peptide made to support your own fullness signaling.*
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.